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Manhattan Infusion Medicine
Dedicated to Your Comfort & Well-being
At our private and comfortable Midtown East office we offer infusion therapies for:
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Chronic Depression
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Chronic Pain Syndromes
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Chronic Stress Reduction
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Virus Immunity Support
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Cognition & Memory Support
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Migraine Relief
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Jet-Lag Relief
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Hangover Relief
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Athlete’s Endurance Support
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Vegetarian Supplement Support
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Complexion & Hair Health
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Anti-Aging/Antioxidant Support
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Doctor Prescribed IV Medications
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Custom Infusions Available
Consultation by appointment at our private medical suite, your home, office, hotel, or Zoom
Manhattan Infusion Medicine
(646) 877-2218

About Infusion Therapy
Manhattan Infusion Medicine therapies are specially formulated to provide you with the medicines, vitamins, nutrients, fluids, electrolytes, and anti-oxidants that you need. We provide custom infusions of medicine prescribed for you by your personal physician to treat your medical condition and we offer a variety of infusion products to fit your specific lifestyle needs and health goals.
The great advantage of infusion treatment is how fast it can begin to work. Unlike medicines and supplements taken orally, what we deliver by infusion is immediately available to the body.
All infusion therapies are offered in the comfort of our private medical suite. Select infusion therapies may be provided in the privacy of your home, office, or hotel suite. All treatments are managed by board certified physician infusion specialists using advanced monitoring techniques to ensure your safety and comfort.
Learn About: Chronic Illness Infusions
CHRONIC DEPRESSION INFUSION
Ketamine has been an FDA approved anesthetic since the 1970s. More recently, low dose IV Ketamine infusions have been effectively used to treat chronic depression. An advantage of IV Ketamine infusion treatment is its potential for rapid action at brain receptor sites. One of these is the N-methyl-D-aspartate (NMDA) receptor found on gamma-aminobutyric acid (GABA) neurons. These receptors stimulate the neural signaling and synaptic plasticity that are thought to underlie the antidepressant benefits of Ketamine.
COGNITIVE-MEMORY INFUSION
Improve how you feel and support memory function with IV hydration, multiple vitamin infusions, and nicotinamide adenine dinucleotide (NAD+). NAD+ is a coenzyme found in all living cells and is required for some of our fundamental biological processes. NAD+ has been shown to decline in the aging human brain. Ketamine may also be useful. Ketamine stimulates the growth of new brain cell connections, enhancing the neuroplasticity of the brain. This may help in treating mild cognitive decline (MCD) when treatments are combined with post-infusion cognitive training programs and cognitive behavioral therapy.
CHRONIC PAIN SYNDROME INFUSION
Low dose IV Ketamine infusions are effective as one part of treatments for chronic pain syndromes. Ketamine acts on the NMDA receptors found on the brain’s GABA neurons. These neurons are involved in transmitting and modulating pain signals. The action of Ketamine on these neural pathways are thought to underly its chronic pain reduction effects.
MIGRAINE RELIEF INFUSION
Improve how you feel with our rapid response migraine relief infusion in the comfort and privacy of your home, hotel, or our private medical suite. This treatment is designed to relieve migraine symptoms. It is most effective when it is administered during the early signs of a migraine headache. A preventative infusion treatment is also a good option when a known trigger activity such as planned air travel is anticipated.
Well-Being Elevation Infusions
COMPLEXION/HAIR HEALTH INFUSION
Complexion and hair health are greatly affected by exposures to harsh chemicals, dietary deficiencies, and the effects of aging. This infusion supplies hydration, Vitamins B, E, A, and other important vitamins, anti-inflammatory agents, and antioxidants to improve and enhance complexion and hair health.
VIRUS IMMUNITY SUPPORT INFUSION
This infusion is helpful for teachers, frequent travelers, and medical workers who are frequently exposed to common viral contagions. It provides hydration, Vitamin B-complex, Vitamin C, Amino Acids, Zinc, Copper, Manganese, Chromium, and Selenium. If you are coming down with a common cold this therapy can help reduce its severity and duration especially if administered in the first 24 hours after your symptoms start.
CHRONIC STRESS INFUSION
Chronic stress is a serious physical and psychological health risk. Our infusion, combined with relaxation exercises, can help. It has amino acids, GABA, taurine, theanine, B12, and the “relaxation” mineral magnesium to help with your mental and physical relaxation.
ANTI-AGING/ANTI-OXIDANT INFUSION
Improve how you feel with powerful anti-oxidizing agents and IV hydration. Molecules called free radicals can cause damage to healthy cells in our body leading to premature skin aging and diseases. Limiting free-radical injury by scavenging free radical electron groups is the natural process of our body’s antioxidants. Our infusion is a blend of IV fluid, electrolytes, vitamin C, and glutathione that helps assist the body in reducing the damage caused by these free radicals.
Lifestyle Repletion Infusions
HYDRATION INFUSION
Whether dehydrated from a strenuous physical workout routine, from fighting a winter cold, or from the hot summer weather, don’t wait 20 hours in an ER or be uncomfortable at an urgent care center. Quickly rehydrate in comfort and privacy. This treatment includes one liter of IV hydration with electrolytes
HANGOVER RELIEF INFUSION
This infusion therapy delivers IV hydration with added medications that reduce feelings of fatigue following physically debilitating activities. It is especially helpful when late nights, fast food, and long stressful work hours combine to cause dehydration, inflammation, and a loss of nutrients. Don’t let that fatigue hang over you the whole next day. Get back to being yourself quickly with this treatment package that includes
JET-LAG RELIEF INFUSION
Improve how you feel with this jet-lag therapy. Jet lag, technically know as desynchronosis, is a sleep disorder that can affect those who travel often and cross time zones. Frequent travel across time zones can make you feel like its time to sleep when its time to work. Get back to feeling normal again more quickly.
VEGETARIAN NUTRITION INFUSION
Important to achieving good health and longevity is a balanced diet. Vegan and vegetarian diets can be beneficial for health, but may also result in nutrient deficiencies. There are plenty of plant nutrient sources such as lentils, beans, chickpeas, nuts, seeds, soy products, and whole grains. But during our rushed daily lifestyles, finding specialty foods and preparing them to create that healthy balanced diet can be a challenge. Healthy vegan and vegetarian diets can efficiently be achieved with our infusion therapy.
Learn More and Schedule Online

About Dr. Calabrese
Mission: To support our medical care team with the highest quality patient care and professionalism.
24 years of clinical experience
Stanford University Anesthesiologist MD
PhD Cognitive Science
MA Cognitive Psychology
MA Social Psychology
InstructorAdvanced Cardiac Life Support
Certified Medical First Responder
John F. Calabrese, MD, PhD, MA
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